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it is a chronic disease characterized by a drug seeking and use that is compulsive or difficult to control despite harmful consequences ​

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Answer:

Drug addiction is a chronic disease characterized by drug seeking and use that is compulsive, or difficult to control, despite harmful consequences. Brain changes that occur over time with drug use challenge an addicted person's self-control and interfere with their ability to resist intense urges to take drugs.

-Furikit

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